Analysis of Adverse Reactions of Azithromycin in Pediatric Clinical Application

Jia-Xin Huang

Abstract

Objective: this study mainly discusses the adverse reactions of azithromycin in the clinical treatment of pediatrics. Methods: 400 cases of children with infectious diseases treated in our hospital from March 2020 to December 2021 were selected as the main subjects of the study, and were arbitrarily divided into the observation group and the control group, with 200 cases in each group. The children in the observation group were divided into intravenous drip group (91 cases) and oral group (109 cases) according to the medication. Children in the control group were treated with antibiotics other than azithromycin, and children in the observation group were treated with azithromycin. The children in the intravenous drip group were treated with azithromycin intravenous drip, and the children in the oral group were treated with azithromycin extended-release tablets. Comparison of adverse reactions between the observation group and the control group, intravenous drip group and oral group. Results: The incidence of adverse reactions in the observation group was much higher than that in the control group (19.0%, 10.5%, respectively), and the difference was statistically signifcant (P < 0.05). Gastrointestinal reactions, followed by allergic symptoms, were the most common among the children in both groups. The incidence of adverse reactions was 18.68% in the intravenous drip group and 19.27% in the oral group, which was not signifcant (P > 0.05). Conclusion: azithromycin has many adverse reactions in pediatric use. When applying azithromycin in clinical medicine, the scope of application should be strictly grasped, and drug monitoring and observation should be improved during the medication period, so that adverse reactions can be detected as soon as possible, and then solved by symptomatic treatment.

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