Journal of Clinical Medicine and Research http://ojs.omniscient.sg/index.php/cmr <p><strong><em>Journal of Clinical Medicine and Research</em></strong> (Print:3060-8708 Online:3060-8694)is an open access, international academic journal aimed at promoting the latest research and discoveries in the field of clinical medicine. The journal covers a wide range of clinical medical topics, including but not limited to disease diagnosis and treatment, clinical trials, epidemiology, medical imaging, surgical procedures, drug therapy, and medical education. The "Journal of Clinical Medicine and Research" is committed to providing high-quality original research articles, reviews, and case reports, offering updated clinical practice guidelines and the latest medical knowledge to medical professionals. The goal of the journal is to become a leading publication in the field of clinical medicine, contributing to the advancement and innovation of the medical community.</p> Omniscient Pte. Ltd. en-US Journal of Clinical Medicine and Research Analysis of Adverse Reactions of Azithromycin in Pediatric Clinical Application http://ojs.omniscient.sg/index.php/cmr/article/view/40499 <p>Objective: this study mainly discusses the adverse reactions of azithromycin in the clinical treatment of pediatrics. Methods: 400 cases of children with infectious diseases treated in our hospital from March 2020 to December 2021 were selected as the main subjects of the study, and were arbitrarily divided into the observation group and the control group, with 200 cases in each group. The children in the observation group were divided into intravenous drip group (91 cases) and oral group (109 cases) according to the medication. Children in the control group were treated with antibiotics other than azithromycin, and children in the observation group were treated with azithromycin. The children in the intravenous drip group were treated with azithromycin intravenous drip, and the children in the oral group were treated with azithromycin extended-release tablets. Comparison of adverse reactions between the observation group and the control group, intravenous drip group and oral group. Results: The incidence of adverse reactions in the observation group was much higher than that in the control group (19.0%, 10.5%, respectively), and the difference was statistically signifcant (P &lt; 0.05). Gastrointestinal reactions, followed by allergic symptoms, were the most common among the children in both groups. The incidence of adverse reactions was 18.68% in the intravenous drip group and 19.27% in the oral group, which was not signifcant (P &gt; 0.05). Conclusion: azithromycin has many adverse reactions in pediatric use. When applying azithromycin in clinical medicine, the scope of application should be strictly grasped, and drug monitoring and observation should be improved during the medication period, so that adverse reactions can be detected as soon as possible, and then solved by symptomatic treatment.</p> Jia-Xin Huang Copyright (c) 2024 Journal of Clinical Medicine and Research 2024-08-19 2024-08-19 1 1 Analysis of the Influence of Pharmacy Guidance on Medication Adherence of Diabetic Patients http://ojs.omniscient.sg/index.php/cmr/article/view/40500 <p>Pharmacy guidance is an important way of medical service, which has a positive impact on improving medication adherence of diabetic patients. The role of pharmacy guidance is mainly to improve patients’ medication adherence by promoting patients’ understanding of drugs, standardizing patients’medication behavior, enhancing patients’ initiative and self-management ability, and strengthening communication and trust between doctors and patients. Pharmacy guidance can enable patients to better understand drugs, establish the correct concept of drug use, and avoid the risks associated with improper drug use. In addition, pharmacy guidance can also improve patients’self-management ability and self-control awareness, so that patients can take more initiative to control the disease and achieve better therapeutic effects. Therefore, pharmacy guidance plays a very important role in improving medication adherence of diabetic patients and is worth to be widely carried out in clinical practice.</p> Hua Wei Copyright (c) 2024 Journal of Clinical Medicine and Research 2024-08-19 2024-08-19 1 1 Current Status and Research Progress of Surgical Treatment of Thyroid Tumors http://ojs.omniscient.sg/index.php/cmr/article/view/40501 <p>With the progress of modern medicine, the level of clinical diagnostic technology in China has been promoted. Thyroid tumor is one of the more common lesions in general surgery, but in recent years, the incidence of thyroid tumor is also getting higher and higher, endangering the health of the general public. The diagnostic means of thyroid tumors are also diversifed, and at present, modern medicine mostly carries out diagnosis for patients through surgical diagnosis and treatment, but at present, bipolar electrocoagulation is used for postoperative diagnosis with the advantages of good curative effect, less incidence of postoperative complications in patients, and little diffculty in postoperative operation.</p> Xue-Song Wu Copyright (c) 2024 Journal of Clinical Medicine and Research 2024-08-19 2024-08-19 1 1 Study on the Effect of Anesthesia Application of Nalbuphine Hydrochloride Combined with Propofol in Painless Gastroscopy http://ojs.omniscient.sg/index.php/cmr/article/view/40502 <p>In recent years, with the increase of patients with gastric disease, gastric examination has become more important, painless gastroscopy is very common in medicine, and the drugs with fast effect and safety are the most commonly used drugs nowadays. Among them, propofol injection has fast effect and quick awakening, which is suitable for painless gastroscopy, but it has certain limitations, and its shortcomings are mainly refected in the serious suppression in the whistle drug, and the required dosage is large, and currently the clinical application of composite opium and other analgesic drugs in order to minimize the adverse reactions and reduce the consumption of propofol.</p> Wei-Lai Zhou Copyright (c) 2024 Journal of Clinical Medicine and Research 2024-08-19 2024-08-19 1 1 Symptoms and Common Treatment of Pneumonia in Children http://ojs.omniscient.sg/index.php/cmr/article/view/40504 <p>Pneumonia, as the frst cause of pediatric hospitalization mortality in China, is in fact a serious threat to the health of children, and it is very important to strengthen the prevention and treatment of this disease. If in daily life, parents fnd that their children show symptoms of childhood pneumonia, they should take them to the hospital for examination and treatment immediately. Due to the diverse causes of childhood pneumonia and the complexity of its treatment, parents should not use medication on their own to deal with it. The purpose of this article is to explore the symptoms of childhood pneumonia and common treatment methods to provide relevant knowledge interpretation for children with pneumonia.</p> Hong Zhang Copyright (c) 2024 Journal of Clinical Medicine and Research 2024-08-19 2024-08-19 1 1