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Assessment of the Diagnostic and Prognostic Efficacy of Combined Detection of Serum Tumor Markers in Patients with Lung Cancer

Xiu-Qin Chang

Xiao-Mei Hai

Jing Liu

https://doi.org/10.37155/2717-5278-0502-8

Abstract

Objective: To analyze the application effectiveness of combined detection of serum tumor markers (TM) in lung cancer. Methods: Forty cases of lung cancer patients admitted in recent years were included in the observation group A, 50 cases of patients with benign lung lesions were included in observation group B,and 55 cases of healthy examinees during the same period were included in the control group. TM was tested in all three groups, and the diagnostic efficacy was compared. Results: The levels of CYFRA21-1, CA125, NSE,SCC, and CEA in the control group, observation group B, and group A showed an increasing trend (P < 0.05);the positivity rates of CYFRA21-1 and SCC were the highest in squamous cell carcinoma, while the positivity rates of CA125 and CEA were the highest in adenocarcinoma, and the positivity rate of NSE was the highest in small cell lung cancer (P < 0.05). The accuracy and sensitivity of the five-item combined test were higher, and the specificity of CYFRA21-1 test was higher (P < 0.05). Conclusion: When clinically examining lung cancer, combined detection of TM can effectively detect lung cancer with high diagnostic efficacy, which has promotional value.

Keywords

Serum markers; Lung cancer; Diagnosis; Benign lung lesions

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