Research on Targeted FAP Boron Drugs for the Treatment of Pancreatic Cancer
Long-Hai Wu
Abstract
Pancreatic cancer has a low five-year survival rate and poses a significant threat, with high resistance to traditional chemotherapy drugs and clinical treatment difficulties. This article mainly analyzes the impact of miR-30a-5p and 10B-FAPI on inhibiting pancreatic cancer.
Keywords
miR-30a-5p; 10B-FAPI; pancreatic ductal adenocarcinoma; targeted therapy; boron neutron capture imagingFull Text
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[1] Looi CK, Chung FF, Leong CO, et al. Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment. J Exp Clin
Cancer Res. 2019;38(1):162.
[2] Huang H, Li W, Zhang MK, Sun ZK, Li YB, Guo ZY, Li YM. Mechanism of microRNA-30a-5p activating Wnt/β-catenin signaling pathway on proliferation and invasion of gastric cancer cells. Chin J Exp Surg. 2023;40(5):863-866.
[3] He Y, Dong BL, Wang XX, Li Y, Yang XJ. miR-30a-5p targets fibroblast activation protein-1 to inhibit proliferation and migration of pancreatic ductal adenocarcinoma. J Lanzhou Univ (Med Sci). 2023;49(3):5-11.
[4] Xia JH, Zhou LQ, Yan Y, Ma TT, Su XY. miR-30a-5p regulates invasion and migration of lung adenocarcinoma cells by inhibiting ECM receptor interaction signaling pathway-related proteins.Zhejiang Med J. 2023;45(1):21-27.
[5] Zhang DL, Liang SB, Wei W, Zhuang Y, Zhang K. Serum miR-30a-5p affects the development of knee osteoarthritis by targeting FOXD1. J Guangxi Med Univ. 2023;40(2):282-287.
[6] Ni MQ, Wu S, Jin CT, Tian M. Clinical application of 68Ga-FAPI PET/CT in malignant tumors. Int J Radiat Med Nucl Med. 2021;45(05):305-312.
[7] Wang XW, Tang JT. Tumor particle therapy engineering technology. China Science and Technology Press. 2022:69-72.
[8] Zhou L, Jia S, Chen Y, et al. The distinct role of CD73 in the progression of pancreatic cancer. J Mol Med (Berl). 2019;97(6):803-815.
Cancer Res. 2019;38(1):162.
[2] Huang H, Li W, Zhang MK, Sun ZK, Li YB, Guo ZY, Li YM. Mechanism of microRNA-30a-5p activating Wnt/β-catenin signaling pathway on proliferation and invasion of gastric cancer cells. Chin J Exp Surg. 2023;40(5):863-866.
[3] He Y, Dong BL, Wang XX, Li Y, Yang XJ. miR-30a-5p targets fibroblast activation protein-1 to inhibit proliferation and migration of pancreatic ductal adenocarcinoma. J Lanzhou Univ (Med Sci). 2023;49(3):5-11.
[4] Xia JH, Zhou LQ, Yan Y, Ma TT, Su XY. miR-30a-5p regulates invasion and migration of lung adenocarcinoma cells by inhibiting ECM receptor interaction signaling pathway-related proteins.Zhejiang Med J. 2023;45(1):21-27.
[5] Zhang DL, Liang SB, Wei W, Zhuang Y, Zhang K. Serum miR-30a-5p affects the development of knee osteoarthritis by targeting FOXD1. J Guangxi Med Univ. 2023;40(2):282-287.
[6] Ni MQ, Wu S, Jin CT, Tian M. Clinical application of 68Ga-FAPI PET/CT in malignant tumors. Int J Radiat Med Nucl Med. 2021;45(05):305-312.
[7] Wang XW, Tang JT. Tumor particle therapy engineering technology. China Science and Technology Press. 2022:69-72.
[8] Zhou L, Jia S, Chen Y, et al. The distinct role of CD73 in the progression of pancreatic cancer. J Mol Med (Berl). 2019;97(6):803-815.
Copyright © 2024 Long-Hai Wu
Publishing time:2024-02-27
This work is licensed under a Creative Commons Attribution 4.0 International License
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