The Efficacy and Safety Analysis of Opioid Analgesics in the Treatment of Pain in Elderly Patients with Malignant Tumors and Cancer Pain

Wen-Juan Feng

Abstract

Objective: To investigate the efficacy and safety of opioid analgesics in the treatment of pain in elderly patients with malignant tumors and cancer pain. Methods: 108 cases of malignant tumor patients admitted to our hospital from March 2022 to December 2023 were selected as the research subjects. Opioid analgesics such as codeine, hydrocodone, fentanyl, methadone, tramadol, and morphine were used for analgesia, and the analgesic effect and safety were analyzed. Results: The pain of patients was relieved and improved compared to before treatment, and the differences in the comparison results were statistically significant (P < 0.05). The types of adverse reactions included dizziness, nausea and vomiting, somnolence, respiratory depression, etc. The total incidence rates of adverse reactions with four or more drugs were 11.11%,7.41%, 6.48%, and 8.33%, respectively, and the comprehensive incidence rate of adverse reactions was 47.22%.Conclusion: Analgesic treatment for elderly patients with malignant tumors and cancer pain can be selected according to the category of drugs, which can effectively improve and alleviate the level of pain. However,various adverse reactions are prone to occur, so medication should be used cautiously and appropriate types of drugs should be selected according to the patient's condition.

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