Effectiveness and Safety of Combined Chemotherapy and Biological Targeted Therapy in the Treatment of Breast Cancer

Qi-Yu  Zhao

Effectiveness and Safety of Combined Chemotherapy and Biological Targeted Therapy in the Treatment of Breast Cancer

Qi-Yu Zhao （ Shenyang Pharmaceutical University,Shenyang, Liaoning,110016,China ）

https://doi.org/10.37155/2717-5278-0602-4

Abstract

Purpose: To evaluate the effectiveness and safety of combined chemotherapy and biological targeted therapy in breast cancer patients. Methods: Atotal of 72 patients diagnosed with breast cancer confrmed by pathological examination and hospitalized from February 2023 to February 2024 were selected. They were randomly divided into two groups using systematic randomization: control group (n = 36) and observation group (n = 36). The control group received chemotherapy, while the observation group received combined chemotherapy and biological targeted therapy. The incidence of complications and quality of life scores were compared between the two groups. Results: After treatment, the incidence of complications in the observation group was lower compared to the control group (11.11% vs. 30.56%, P < 0.05). There was no significant difference in quality of life indicators between the two groups before treatment (P > 0.05). However, after treatment, the quality of life scores in the observation group were signifcantly higher compared to the control group (P < 0.05). Conclusion: Combined chemotherapy and biological targeted therapy in breast cancer patients have remarkable effects in improving local recurrence, preventing distant metastasis, and enhancing overall quality of life with high safety. This approach holds signifcant value for reference and promotion.

Keywords

Chemotherapy; Biological targeted therapy; Breast cancer; Effectiveness; Safety.

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Publishing time:2024-04-30
This work is licensed under a Creative Commons Attribution 4.0 International License