阻塞性睡眠呼吸暂停与高血压的研究进展
张晓玲 ( 暨南大学附属珠海医院(珠海市人民医院) )
冯颖青* ( 暨南大学附属珠海医院(珠海市人民医院) )
https://doi.org/10.37155/2661-4766-0606-48Abstract
阻塞性睡眠呼吸暂停综合征作为高血压的独立危险因素,其在人群中的发病率不断上升,与高血压可能 存在相互影响的关系,OSA患者睡眠紊乱引起交感神经活性增强以及间歇性低氧。目前OSA的治疗方式多样,需要更 加个体化的治疗方案以适应不同患者的具体病情、生理特点、生活方式。
Keywords
阻塞性睡眠呼吸暂停;高血压;生理机制;治疗方向Full Text
PDFReferences
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respiratory medicine, 2019,7(8):687-698.
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高血压合并阻塞性睡眠呼吸暂停低通气综合征患者发生
动脉硬化风险预测模型的建立与验证[J]. 中国现代医学杂
志, 2024,34(18):48-56.
[3]Loh H H, Lim Q H, Chai C S, et al. Influence
and implications of the renin-angiotensin-aldosterone
system in obstructive sleep apnea: An updated systematic
review and meta-analysis.[J]. Journal of sleep research,
2023,32(1):e13726.
[4]Gras E, Belaidi E, Briançon-Marjollet A, et al.
Endothelin-1 mediates intermittent hypoxia-induced
inflammatory vascular remodeling through HIF-1 activation.
[J]. Journal of applied physiology (Bethesda, Md. : 1985),
2016,120(4):437-443.
[5]Durgan D J, Ganesh B P, Cope J L, et al. Role of
the Gut Microbiome in Obstructive Sleep Apnea-Induced
Hypertension.[J]. Hypertension (Dallas, Tex. : 1979),
2016,67(2):469-474.
Copyright © 2024 张晓玲,冯颖青* Publishing time:2024-12-31
This work is licensed under a Creative Commons Attribution 4.0 International License