冠状动脉支架内再狭窄病理机制研究新进展

郑 刚 ( 天津市泰达心血管病医院互联网医院 )

徐延敏 ( 天津医科大学第二医院CCU科 )

https://doi.org/10.37155/2717-5693-0303-32

Abstract

药物洗脱支架技术的引入及其后续迭代大大提高了经皮冠状动脉介入治疗的疗效和安全性。然而,支架内 再狭窄( ISR)的发生率以及由此导致的重复血运重建的需要仍以每年1%-2%的速度发生。鉴于全球每年有数百万药物洗 脱支架植入, ISR可以被视为具有公共卫生意义的病理实体。 ISR的机制是多因素的。自从首次描述ISR的血管造影模式以 来,冠脉内成像的出现进一步阐明了ISR的机制和模式。 ISR的医疗设备和治疗策略也随着时间的推移而发展。目前,推 荐使用冠状动脉内成像来表征ISR底层基底的个性化方法。在本文中,我们全面回顾了ISR的发病率和机制。

Keywords

冠状动脉;支架再狭窄;病理机制

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