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CuO Nanowhiskers Grown from Cu Nanowire Electrode as Highly Efficient Electrocatalysts for Glucose Detection

Zebin Xue （ College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 300014, China. ）

Jihong Liang （ College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 300014, China. ）

Zongjian Liu （ College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 300014, China. ）

https://doi.org/10.37155/2717-526X-0601-4

Abstract

Nonenzymatic electrochemical glucose sensors are normally based on an electrode that owns a conductive substrate decorated with nanosized electrocatalysts. However, these sensors often suffer from drawbacks originating from the use of polymer binder or substrate of low specific surface area. In this work, a porous Cu nanowire (CuNW) electrode fabricated by thermal annealing of CuNWs is employed as the conductive substrate, and the electrocatalysts, namely CuO nanowhiskers with a length ranging from 1 μm to 2 μm, are in situ grown from the CuNW electrode via anodic deposition and subsequent calcination. Electrochemical measurements by cyclic voltammetry indicate that the as-formed electrode is stable in alkaline medium and responds well to the addition of glucose. An investigation on the performance of this CuO nanowhiskers/CuNWs electrode as a nonenzymatic glucose sensor via amperometry under optimized conditions reveals a wide linear range of 3 μM to 7135 μM, a high sensitivity of 3506 μA·mM-1·cm-2, and a low detection limit of 0.96 μM at a signal-to-noise ratio of 3. Testing the interfering signals produced by Cl- ions and some easily oxidizable compounds at a level of physiological concentration suggests a strong anti-interference ability of the as-prepared sensor. In addition, this new glucose sensor also possesses good stability and reproducibility and is successfully tested for detection of glucose in human serum sample.

Keywords

Cu nanowires; CuO nanowhiskers; Electrocatalysts; Glucose; Nonenzymatic sensor

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References

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