Vol 2 No 1 (2020)

• Diagnostic Value of Electrocardiogram(ECG) in Aortic Dissection Aneurysm

  Jingxia Zhai, Junkang Ye

  Objective: To explore and analyze the diagnostic value of electrocardiogram(ECG) in aortic dissection aneurysm. Method: From February 2018 to September 2019, 80 patients with suspected aortic dissection aneurysm received in our hospital were selected, 30 patients were examined by ECG, 30 patients were examined by CT, and 20 patients were examined by echocardiography. The diagnostic standard is digital subtraction angiography, and the value of ECG in the diagnosis of aortic dissecting aneurysms is analyzed. Result: Compared with ECG, the diagnosis of aortic dissecting aneurysm by CT and echocardiography has more obvious advantages in sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. Conclusion: The application of ECG in the diagnosis of aortic dissecting aneurysm has a lower clinical value than CT and echocardiography, but the ECG has the characteristics of non-invasive and fast, and can be used in the emergency of aortic dissecting aneurysm.

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• Diagnostic Value of Conventional MRI and DWI for Atypical Primary Central Nervous System Lymphoma(PCNSL)

  Xinyan Yang

  Objective: To apply conventional Magnetic Resonance Imaging (MRI) and Diffusion-Weighted Imaging (DWI) to patients with atypical Primary Central Nervous System Lymphoma (PCNSL), and analyze its diagnostic value. Method: We selected 18 patients with atypical PCNSL who had been treated in our hospital from January 2018 to December 2019. All patients underwent conventional MRI and DWI, and we analyzed their MRI and DWI performance. Results: There were 24 lesions among the 18 patients in this group. MRI showed that the lesions were mostly in low signal on T1WI (83.33%), high signal on T2WI (83.33%), some with clear boundaries (62.5%), and some involved the midline structure or ventricles (62.5%). The single lesions were mostly nodular or mass-like enhancements (41.67%), and the multiple lesions were mostly ring-shaped enhancements (29.17%). DWI showed tumor epithelial high signal (54.17%) or slightly high signal (33.33%). The ADC value and rADC of tumor epithelial area, proximal and distal edema area around the tumor were significantly different (P<0.05). Conclusion: Conventional MRI and DWI showed obvious imaging characteristics of atypical PCNSL, with high diagnostic value.

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• Analysis of Retropubic and Laparoscopic Radical Prostatectomy for Localized Prostate Cancer

  Lijun Yang, Huajing Ha, Bingyi Li

  Objective：To analysis of treatment effects and safety of retropubic approach and laparoscope approach of radical prostatectomy in localized prostate cancer. Methods：The observation group underwent radical prostatectomy by laparoscope approach,while the control group underwent radical prostatectomy by retropubic approach, after that, to analysis the operation indexes and complications of patients. Results：The intraoperative blood loss,length of stay and postoperative NRS score of observation group were less than control group, the operation time of the observation group was longer than that of the control group. with statistical significance (P＜0.05). The postoperative complication rate of observation group was lower than control group,with statistical significance (P＜0.05). Conclusion：Comparing with retropubic approach, laparoscope approach of radical prostatectomy for localized prostate cancer can improve the safety of surgical treatment and optimize surgical indicators,which is worthy of promotion.

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• Analysis of Pain Assessment and Nursing Measures for Patients with Advanced Hematological Tumors

  Min Shao

  Objective: To analyze the pain assessment results and nursing measures and its effects on patients with advanced hematological tumors. Methods: Select 50 patients with advanced hematological tumors admitted to our hospital from January 2017 to January 2019, evaluating their pain levels when implementing pain care. Results: Among 50 patients with advanced hematological tumors, mild pain was 6.00%, moderate pain was 50.00%, and severe pain was 44.00%. The quality of life scores was increasing while the pain level assessment, Pittsburgh sleep quality index and mental state scores decreased after the implementation of pain care. The difference was statistically significant (P<0.05). Conclusion: Moderate and severe pain is common in patients with advanced hematological tumor. Considerate pain care is helpful to relieve pain, improve sleep quality and mental state.

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• Virulent Bacteria as A Co-factor of Colon Carcinogenesis: Evidence from Two Monozygotic Patients Virulent bacteria in CRC

  Iradj Sobhani, Emma Bergsten, Cecile Charpy, Denis Mestivier

  Colorectal carcinoma (CRC) is a common disease with a poor prognosis. CRC results from the accumulation of DNA alterations in colonocytes through a multistage carcinogenesis process. Most CRCs are related to the environment, which influences microbiota composition in the colon. Here we report the analysis of the gut microbiota of two monozygotic twin sisters, one of whom suffering from advance colorectal tumor-infiltrated by immunotolerant T cells. Comparative analysis highlights the profound disequilibrium of the composition of the gut microbiota of CRC-displaying twin with overexpression of virulent bacteria such as E. coli, Shigella, and Clostridium species in the CRC patient’s feces in contrast with low level of bacterial species such as Faecalibacterium and Akkermansia usually enriched in the healthy adults’ microbial flora at the expense of an over-representation of pathogenic bacterial species. The disequilibrium in microbiota of the CRC patient’s feces as compared to her monozygotic twin sister is linked with inflammatory and immune cell infiltrate in the patient’s tumor tissue.

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