低温等离子射频术联合聚桂醇注射在成人咽喉海绵状血管瘤治疗中的疗效分析
朱 娱 （ 重庆医科大学附属第二医院 ）
https://doi.org/10.37155/2717-5669-0502-25Abstract
目的：探讨低温等离子射频术联合聚桂醇注射治疗咽喉部海绵状血管瘤的疗效。方法：研究了60例咽喉 部海绵状血管瘤患者，分为治疗组和对照组，治疗组30例进行了低温等离子射频术联合聚桂醇注射治疗，对照组30 例只进行了聚桂醇注射治疗。随访2年～3年。比较总临床有效率、达到临床有效需要的治疗次数、住院时间、术后不 良反应发生率。结果：治疗组30例总临床有效率100%，其中26例为痊愈，4例显效，对照组总临床有效率76.7%，其 中20例为痊愈，3例显效，总临床有效率差异有统计学意义（P < 0.05）。治疗组经过1次治疗全部有效，对照组达到 有效需要的手术次数为（1.83±0.66）次，差异有统计学意义（P < 0.01）。治疗组住院时间短，平均为（3.10±0.72） 天，对照组住院时间为（8.17±3.96）天，差异有统计学意义（P < 0.01）。治疗组不良反应发生率3.3%（1例），对照 组不良反应发生率23.33%（7例），差异有统计学意义（P < 0.05）。随访2～3年，均未复发。结论：低温等离子射频 术联合聚桂醇注射治疗咽喉部海绵状血管瘤治愈率高，治疗次数减少，不良反应少，值得临床推
Keywords
等离子射频；海绵状血管瘤；聚桂醇Full Text
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Characteristics, Classification, and Management of Adult
Nasopharyngolaryngeal Hemangioma[J]. Laryngosco
pe,2021,131(12):2724-2728.
[3]PaoloAluffiValletti, Andrea Toso, Christel Gorris,
et al. Adult Laryngeal Ossified Hemangioma: Difficulties in
Differential Diagnosis[J].The Journal of Craniofacial Surgery,
2018,29(8):730-732.
[ 4 ] J u n x i a o J i a , J u n b o Z h a n g , S h u i f a n g X i a o .
Clinical Effects of Radiofrequency Coblation for Adult
Laryngopharyngeal Vascular Lesions[J]. Laryngosco
pe,2021,131(3):566-570.
[5]MassimoMesolella, Salvatore Allosso, Gelsomina
Mansueto.Strategies and Controversies in the Treatment With
Carbon Dioxide Laser of Laryngeal Hemangioma: A Case
Series and Review of the Literature[J].Ear, Nose & Throat
Journal,2022,101(5): 326–331.
[6]邱志利,蒋晓平.支撑喉镜下手术切除联合平阳霉素
注射治疗咽喉部较大血管瘤23例[J].山东大学耳鼻喉眼学
报,2014,28(6):53-56.
[7]周智,孙常领,杜晓东,等.成人咽喉部血管瘤23
例临床分析[J].中国中西医结合耳鼻咽喉科杂志,2020,
28(2):124-126,130.
[8]Iwata N, Hattori K, Nakagawa T, et al. Hemangioma
of the nasal cavity[J]. Auris Nasus Larynx,2002,29:335-339.
[9]Griauzde J, Srinivasan A. Imaging of vascular
lesions of the head and neck[J]. RadiolClinNorth Am.
2015;53(1):197-213.
[10]Zheng JW, Zhou Q, Yang XJ, et al. Treatment
guideline for hemangiomas and vascular malformations of the
head and neck[J]. Head Neck, 2010, 32(8):1088-98.
[11]Huang CM, Lee KW, Huang CJ. Radiation
therapy for life-threatening huge laryngeal hemangioma
involving pharynx and parapharyngeal space[J]. Head Neck,
2013,35(4):E98-101.
[12]Hye-kyung Shim, Mi Ra Kim.Potassium-Titanyl_x0002_Phosphate (KTP) Laser Photocoagulation Combined with
Resection Using an Ultrasonic Scalpel for Pharyngolaryngeal
Hemangioma via a Transoral Approach: Case Report and
Literature Review[J].Am J Case Rep, 2021,22: e931042.
[13]吴仲杰,张英.低温等离子消融术治疗智齿冠周炎
临床观察[J].基层医学论坛,2020, 24(8):2.
[14]肖水芳,张俊波. 进一步规范化推广等离子射频技
术在耳鼻咽喉头颈外科中的应用[J].山东大学耳鼻喉眼学
报,2021,35(2):1-8.
[15]Choby GW, Hwang PH. Emerging roles of coblation
in rhinology and skull base surgery[J]. Otolaryngol Clin North
Am. 2017;50:599-606.
[16]Kamijo A, Hatsushika K, Kanemaru S, et al. Five
adult laryngeal venous malformation cases treated effectively
with sclerotherapy[J]. Laryngoscope.2013,123(11):2766-69
[17]Shou BQ, Shou WD, Yang Z, et al. Clinical analysis
of adverse reaction and complication in treating hemangioma
with PYM[J]. J Clin Stomatol, 2006, 22(3):171-173.
[18]刘雪莱,李忠万.聚桂醇注射液治疗咽喉部血管瘤
[J]. 中国耳鼻咽喉头颈外科,2017, 24(4):4.
[19]Hongyang Qu, Xia Lei, Lin Hu.Successful
Endoscopic Sclerotherapy Using Lauromacrogol Injection
for Laryngopharyngeal Hemangioma[J].Ear, Nose & Throat
Journal, 2021, 100(9) :662–666.
[20]Horbach SER, Lokhorst MM, Saeed P, de Goüyon
Matignon de Pontouraude CMF, Rothov´a A, van der Horst
CMAM. Sclerotherapy for low-flow vascular malformations
of the head and neck: A systematic review of sclerosing
agents. J PlastReconstr Aesthetic Surg. 2016;69(3):295-304.
Copyright © 2024 朱 娱
Publishing time:2024-06-30
This work is licensed under a Creative Commons Attribution 4.0 International License
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