Vol 6 No 1 (2024)

• Observation of Clinical Treatment Efficacy in Severe Heart Failure of Geriatric Cardiology

  Qi Yuan

  Objective: To explore the clinical treatment efficacy of severe heart failure in geriatric cardiology.Methods: A total of 122 cases of severe heart failure patients admitted to our hospital from January 2022 to December 2023 were selected as the research subjects. The patients were divided into two groups using digital random grouping method, with 61 cases in each group. The control group was treated with metoprolol, while the experimental group was treated with metoprolol combined with eplerenone hydrochlorothiazide. The occurrence rate of adverse reactions and treatment efficacy of clinical indicators were compared between the two groups.Results: There was no significant difference in the incidence of adverse reactions (P > 0.05); the clinical indicators of the experimental group were better than those of the control group, and the total effective rate of treatment was higher than that of the control group. The difference in comparison results was statistically significant (P < 0.05). Conclusion: For the treatment of severe heart failure in geriatric patients in cardiology,metoprolol combined with eplerenone hydrochlorothiazide can be used, which can significantly improve the clinical signs of patients, increase the total effective rate of treatment, and will not significantly increase the risk of adverse reactions. It is worth further promotion and application.

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• The Efficacy and Safety Analysis of Opioid Analgesics in the Treatment of Pain in Elderly Patients with Malignant Tumors and Cancer Pain

  Wen-Juan Feng

  Objective: To investigate the efficacy and safety of opioid analgesics in the treatment of pain in elderly patients with malignant tumors and cancer pain. Methods: 108 cases of malignant tumor patients admitted to our hospital from March 2022 to December 2023 were selected as the research subjects. Opioid analgesics such as codeine, hydrocodone, fentanyl, methadone, tramadol, and morphine were used for analgesia, and the analgesic effect and safety were analyzed. Results: The pain of patients was relieved and improved compared to before treatment, and the differences in the comparison results were statistically significant (P < 0.05). The types of adverse reactions included dizziness, nausea and vomiting, somnolence, respiratory depression, etc. The total incidence rates of adverse reactions with four or more drugs were 11.11%,7.41%, 6.48%, and 8.33%, respectively, and the comprehensive incidence rate of adverse reactions was 47.22%.Conclusion: Analgesic treatment for elderly patients with malignant tumors and cancer pain can be selected according to the category of drugs, which can effectively improve and alleviate the level of pain. However,various adverse reactions are prone to occur, so medication should be used cautiously and appropriate types of drugs should be selected according to the patient's condition.

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• Management and Nursing Optimization for Patients with Abdominal Aortic Aneurysm during the Perioperative Period

  Guan Wang

  Objective: To analyze the management and nursing measures and effects during the perioperative period of patients with abdominal aortic aneurysm. Methods: A total of 48 patients with abdominal aortic aneurysm admitted to our hospital from February 2023 to February 2024 were selected for the study. They were evenly divided into a control group of 24 cases, receiving routine nursing management, and an observation group of 24 cases, receiving high-quality nursing management. The nursing effects of the two groups were compared. Results: The patient satisfaction and knowledge scores in the observation group were significantly higher than those in the control group. The incidence of complications, SAS (Self-Rating Anxiety Scale), and SDS (Self-Rating Depression Scale) scores were significantly lower in the observation group than in the control group (P < 0.05). Conclusion: Providing high-quality nursing management to patients with abdominal aortic aneurysm can improve their psychological status and condition, enhance patient cognition and satisfaction,prevent complications, and has promotional value.

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• Application Experience of High-Quality Nursing Services in Oncology Care

  Sha Wu

  This article aims to explore the application and effects of high-quality nursing services in oncology care. By implementing high-quality nursing services for 100 cancer patients and collecting data through questionnaire surveys and quality of life assessment tools, the impact on patients' quality of life and nursing satisfaction was analyzed. The results showed that high-quality nursing services significantly improved patients' quality of life and nursing satisfaction.

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• New Developments in the Diagnosis and Treatment of Lung Cancer by Respiratory Medicine Physicians

  Aziguli Tuerxun

  With the continuous advancement of medical technology, the diagnosis and treatment methods for lung cancer are constantly evolving. This article aims to explore the new developments in the field of lung cancer diagnosis and treatment by respiratory medicine physicians, including innovations in diagnostic techniques, breakthroughs in treatment methods, and optimization of multidisciplinary collaboration models, in order to provide strong support for improving the survival rate and quality of life of lung cancer patients.

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• The Clinical Study of Acupuncture's Influence on Gastrointestinal Function after Surgery for Benign Gynecological Tumors

  Hai-Jiao Zhang

  Objective: To analyze the influence of acupuncture on gastrointestinal function after surgery for benign gynecological tumors. Methods: A total of 74 patients who underwent surgery for benign tumors from February 2023 to February 2024 in our hospital were selected for the study. They were divided into a control group (n = 37) and an observation group (n = 37) using a random number table method. The control group received conventional intervention, while the observation group received combined acupuncture intervention.The clinical efficacy between the two groups was compared. Results: The MTL (mean transit time) in the observation group was significantly higher than that in the control group, while the levels of VIP (vasoactive intestinal peptide), first flatus, disappearance of abdominal distension, first defecation, and length of hospital stay were significantly lower than those in the control group (P < 0.05). Conclusion: Acupuncture intervention for patients undergoing surgery for benign tumors can effectively improve gastrointestinal function, regulate hormone levels, and prevent adverse reactions, thus having significant value for promotion.

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• Study on the Clinical Value of Preventing Venous Thromboembolism during the Perioperative Period of Gynecological Oncology

  Hui-Qi Bai

  The purpose of this study is to explore the clinical value of preventing venous thromboembolism during the perioperative period of gynecological oncology.Methods: A total of 60 patients voluntarily participated in this study and received diagnosis and treatment (gynecological cancer patients) at our hospital.After signing informed consent, they were divided into two groups for experimental comparison. The study period was from May 2021 to May 2022. The treatment methods were different, but the comparison indicators were the same, with 30 patients in each group. Traditional therapy and low molecular weight heparin sodium therapy were employed. This study used coagulation, fibrinolysis, and postoperative lower extremity deep venous thrombosis formation as controls. Results: By comparing the changes in coagulation function and fibrinolysis system indicators and the incidence of LEDVT after surgery, the observation group showed superiority (P < 0.05).Conclusion: For gynecological cancer patients, low molecular weight heparin sodium therapy can effectively prevent venous thrombosis with significant efficacy.

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• Research on Targeted FAP Boron Drugs for the Treatment of Pancreatic Cancer

  Long-Hai Wu

  Pancreatic cancer has a low five-year survival rate and poses a significant threat, with high resistance to traditional chemotherapy drugs and clinical treatment difficulties. This article mainly analyzes the impact of miR-30a-5p and 10B-FAPI on inhibiting pancreatic cancer.

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• Analysis of the Application Effect of Targeted Nursing Mode in Intracavitary Brachytherapy for Cervical Cancer Patients

  Liang-Ru Liu

  Objective: To analyze the application effect of targeted nursing mode in intracavitary brachytherapy for cervical cancer patients. Methods: A total of 70 cervical cancer patients admitted to our hospital from October 2022 to October 2023 were selected for the study and divided into two groups. All patients received intracavitary brachytherapy, with the control group receiving routine nursing care and the observation group receiving targeted nursing care. The application situations were compared between the two groups.Results: The duration of intracavitary brachytherapy in the observation group was significantly shorter than that in the control group; the overall satisfaction rate of the control group was significantly lower than that of the observation group (P < 0.05).Conclusion: The application of targeted nursing can effectively reduce the duration of intracavitary brachytherapy for patients, and also plays a key role in improving the overall satisfaction of patients, which is beneficial to improve patient prognosis.

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• Analysis of the Application Value of Magnetic Resonance Imaging in the Diagnosis of Intracranial Tumors

  Ming-Jiong Wei, Ling Li, Yan-Zhi Kang, Yu-Xin Zhao, Sheng-Hong Cui

  Objective: To analyze the application effectiveness of magnetic resonance imaging (MRI) in the diagnosis of intracranial tumors. Methods: A study was conducted on 60 patients with intracranial tumors in our hospital from January 2023 to January 2024. All patients underwent both CT scans (included in the control group) and MRI scans (included in the observation group), and the diagnostic efficacy of the two groups was compared. Results: The pathological diagnosis results showed that 63.33% of the tumors were supratentorial and 36.67% were infratentorial. Among them, there were 9 cases of mixed glioblastoma, 4 cases of ependymoma, 7 cases of pleomorphic glioblastoma, 8 cases of astrocytoma, 9 cases of meningioma, 12 cases of pineal gland tumor, and 11 cases of medulloblastoma. The diagnostic accuracy rates of the observation group for supratentorial, infratentorial, and total tumors were significantly higher than those of the control group (P < 0.05). Conclusion: The application of MRI technology in clinical examination can significantly improve the diagnostic efficacy, detect supratentorial and infratentorial tumors, and has promotional value.

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• The Application Value of Color Doppler Ultrasonography in the Differential Diagnosis of Ovarian Tumors

  Jin-Yu Wang

  Objective: To explore the application value of color Doppler ultrasonography in the differential diagnosis of ovarian tumors. Methods: Eighty-six patients with ovarian tumors admitted to our hospital from March 2019 to April 2023 were selected as the research objects. All patients underwent color Doppler ultrasonography, and the diagnostic results, blood flow grading, and blood flow parameters were compared.Results: The diagnostic rates of benign and malignant tumors were 47.67% and 52.33%, respectively. There was a statistically significant difference in the comparison of blood flow grading and blood flow parameters (P < 0.05).Conclusion: The application of color Doppler ultrasonography in the differential diagnosis of ovarian tumors can provide blood flow parameters for the analysis and judgment of benign and malignant tumors, thereby helping doctors better analyze the disease condition. This method is worthy of further promotion and application.

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• A Case of Color Doppler Ultrasound Diagnosis of Carotid Body Tumor

  Chun-Ming Chang

  Carotid body tumor is a rare type of paraganglioma that occurs outside the sheath of the carotid artery, with a predilection for individuals aged 40 to 60, and an equal incidence in both men and women. Due to limited understanding of carotid body tumors, they are often missed or misdiagnosed on ultrasound examination. Although most carotid body tumors grow slowly, their special location in the neck, rich blood supply, and the difficulty of surgery, combined with a certain tendency for malignant transformation, have led to increasing clinical attention to carotid body tumors, making early diagnosis of vital clinical significance. This paper presents a retrospective analysis of a case of carotid body tumor, aiming to explore the diagnostic value of color Doppler ultrasound in the diagnosis of carotid body tumors.

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• Observation of the Clinical Efficacy of Metformin and Pioglitazone in the Treatment of Type 2 Diabetes Mellitus Complicated with Coronary Heart Disease

  Elias Abula, Shan Gao

  Objective: To analyze the application effects of metformin and pioglitazone in the treatment of type 2 diabetes mellitus (T2DM) complicated with coronary heart disease (CHD). Methods: A total of 82 patients with T2DM and CHD from November 2022 to November 2023 were selected for the study. Using a random number table, they were evenly divided into a control group (41 cases treated with pioglitazone) and an observation group (41 cases treated with a combination of metformin and pioglitazone). The clinical efficacy of the two groups was compared. Results: The incidence of adverse reactions in both groups was basically the same (P＞0.05); the observation group showed significantly lower rates of complications, fasting plasma glucose (FPG), 2-hour postprandial glucose (2hPG), glycated hemoglobin (HbA1c), homeostasis model assessment of insulin resistance (HOMA-IR), total cholesterol (TC), triglycerides (TG), and Gensini score than the control group (P＜0.05). Conclusion: Compared with monotherapy, the combined use of pioglitazone and metformin can enhance the clinical efficacy in treating T2DM complicated with CHD, regulate lipid indicators, and has potential for promotion.

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