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  • Eco-friendly Synthesis of Gelatin Nanoparticles Using Genipin as the Crosslinker

    Quoc-Ky Truong, Hien V. Nguyen

    The development of eco-friendly and biocompatible nanoparticle formulations is crucial for advancing sustainable biomedical applications. This study reports the sustainable synthesis of gelatin nanoparticles using the desolvation method, with genipin as a natural crosslinking agent. The effect of genipin concentration on nanoparticle size and polydispersity index (PDI) was investigated, revealing that higher genipin concentrations resulted in reduced particle sizes and improved size uniformity. The optimized formulation exhibited particle size and PDI comparable to gelatin nanoparticles crosslinked with glutaraldehyde, a commonly used but more toxic alternative. Furthermore, transmission electron microscopy (TEM) imaging confirmed relatively spherical morphology of the nanoparticles. The nanoparticles were also shown to be stable in collodial form at 4 °C over 7 days. These findings underscore the potential of genipin-crosslinked gelatin nanoparticles as a sustainable and safer alternative for drug delivery applications.

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  • Synthesis and Application of Some Pheromones and Insect Attractants in Sustainable Agricultural Development in Vietnam

    Chi Hien Dang, Van-Dung Le, Thanh-Danh Nguyen, Van-Nam Dao, Minh-Trong Tran, Thi Yen-Nghi Le, Kim-Thuy Nguyen-Le, Anh-Tuan Nguyen, Nhat-Minh Phan, Dinh-Tri Mai

    This article supplies a review and evaluation of research concerning the synthesis and field application of pheromones and insect attractants in Vietnam, focusing on raising sustainable agricultural development. We present the attractants and pheromones widely tested in Vietnam and Southeast Asia, providing a useful reference for researchers and scientists. Next, we summarize the methods of pheromone synthesis, including compounds with optical and geometric isomeric structures. Finally, the article evaluates the practical effectiveness of using pheromones in pest control in the field, demonstrating the role of Vietnamese scientists in independent research and international cooperation. These results promote environmentally friendly biological solutions and support sustainable agricultural development in Vietnam.

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